DELIVERANCE TRANSDERMAL LOTION

DECADES OF RESEARCH ON A MILLENIUM AGED PROBLEM

DELIVERANCE TRANSDERMAL

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OSTEOARTHRITIC RELIEF WITH AN ADVANCED, ALL NATURAL, TOPICAL, DRUG FREE, POLYPHENOL LOTION THAT WORKS IN MINUTES

Polyphenols AND THE Control of Rheumatoid Arthritis DELIVERANCE MAKES IT POSSIBLE

Rheumatoid arthritis (RA) is a notorious chronic autoimmune inflammatory joint disease, which can cause cartilage and bone damage. This disease is characterized by synovial inflammation, swelling, autoantibody production, cartilage and bone destruction, and systemic features such as cardiovascular, pulmonary, and skeletal disorders. It is associated with progressive disability, systemic complications, early death and socioeconomic costs.

Abstract

Rheumatoid arthritis (RA) is a chronic, systemic, joint-invading, autoimmune inflammatory disease, which causes joint cartilage breakdown and bone damage, resulting in functional impairment and deformation of the joints. The percentage of RA patients has been rising and RA represents a substantial burden for patients around the world. Despite the development of many RA therapies, because of the side effects and low effectiveness of conventional drugs, patients still need and researchers are seeking new therapeutic alternatives. Polyphenols extracted from natural products are effective on several inflammatory diseases, including RA. In this review polyphenols are classified into four types: flavonoids, phenolic acids, stilbenes and others, among which mainly flavonoids are discussed.

Researchers have reported that anti-RA efficacies of polyphenols are based mainly on three mechanisms: their anti-inflammatory, antioxidant and apoptotic properties. The main RA factors modified by polyphenols are mitogen-activated protein kinase (MAPK), interleukin-1β (IL-1β), IL-6, tumor necrosis factor-α (TNF-α), nuclear factor κ light chain enhancer of activated B cells (NF-κB) and c-Jun N-terminal kinases (JNK). Polyphenols could be potent alternative RA therapies and sources for novel drugs for RA by affecting its key mechanisms.

keywords

Rheumatoid arthritis; natural products; polyphenol; flavonoids; phenolic acid; stilbene.

Polyphenols are a class of naturally occurring compounds from botanical sources

Polyphenols are naturally found in fruits, vegetables, herbs, and many other plants. They are produced as secondary metabolites—small molecules created during energy production in plants—and are considered their own category of micronutrients Many polyphenols are degraded by digestive enzymes if taken orally. Dermal absorption ensures an optimum level of activity since the polyphenols bypass digestive degradation and and with our exclusive transdermal absorption process enter the circulatory system and find their way to the brain where they stimulate the release of beta endorphins.

Your body releases endorphins to help you survive. When you feel pain, nerves in your body send pain signals to your brain where Endorphins are released by the hypothalamus and pituitary gland to block the nerve cells that receive the pain signals. This essentially turns off your pain.

The following benefits may result from osteoarthritisxx lotion used regularly

reduce pain and discomfort
attenuate inflammation
may support a healthy immune system
facilitate the healing process

DIRECTIONS FOR USE

Depending on the size of the area you want to start healing, squeeze out about a teaspoon or more, onto that area and massage the lotion onto the skin. The lotion will work where needed regardless of where you rub it on. It is not totally site specific, but blocks pain that is neurogenerated, and can be used for back pain, neck pain muscle pain, knee and joint pains and sports injuries. Where possible apply it to the affected areas. It is also used for chronic headaches migraines menstrual cramps the side effects of cancer treatment, and general nerve discomfort.

USE UP TO 3 TIMES A DAY, AS NEEDED

Contains a blend of multiple polyphenol derivatives and endorphins in a specially formulated transdermal base for optimal absorption. It is safe,painless, and effective